Casting Couch: Rogen Gets Cancer...the Funny Kind

Pineapple Express Dale Robinette/Columbia Pictures

Seth Rogen's kidding around with cancer (and no, we're not kidding).

The Superbad star is going where no funnyman has gone before, signing on for a supporting role in I'm With Cancer, about one man's battle to beat the dread disease.

Hahahahaha...

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Casting Couch: Whitney Heads From Hills to City

Whitney Port INFphoto.com

It's official. MTV today confirmed what we told you about weeks ago: Whitney Port is decamping from The Hills to The City.

The Big Apple-based spinoff from a spinoff finds our heroine trying to launch a career as a fashionista (and scenester) far from home.

"I am thrilled and honored to be in New York City," says Port, "to be able to mature as a young woman both professionally and personally."

But don't expect the 23-year-old maturity seeker to be scrounging for rent money. She's already wrangled a job with famed designer Diane von Furstenberg and been spotted—with camera crew in tow, natch—cavorting about town, such as attending a recent celeb-filled bash hosted by Jermaine Dupri.

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Casting Couch: Fortunas Rise for Dominic Monaghan

Dominic Monaghan Dimitrios Kambouris/WireImage.com

Truth may be stranger than fiction, but no thriller is scarier than our current economic crisis. At least not according to the suits who run Hollywood.

According to the Hollywood Reporter, Dominic Monaghan and Freddy Rodriguez have signed on to star in Fortuna, a horror flick set in the not-too-distant future of 2100, when global economic and climate crises lead to the elimination of the middle class, leaving only the megarich and the severely poverty stricken.

Talk about fingers on the pulse.

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Casting Couch: Carell, Hathaway Remain Employed

Get Smart Warner Bros. Pictures and Village Roadshow Pictures

Steve Carell and Anne Hathaway have spied new jobs, Sarah Jessica Parker is on a hiring spree while hubby Matthew Broderick is back on the boards, and Kristen Bell has a new Boy in her life.

First up, the dynamic duo of Carell and Hathaway. Already on board for a Get Smart sequel, now they have each landed deals that will keep them fiirmly entrenched on Hollywood's A-list.

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Deal Sheet: Heidi Heads Up Victoria's Secret Patrol

Heidi Klum John Shearer/Getty Images

Heidi Klum's latest runway project involves some seriously scantily clad catwalkers: The Victoria's Secret Fashion Show features the likes of Klum, Alessandra Ambrosia, Selita Ebanks, Doutzen Kroes, Adriana Lima, Marisa Miller and Miranda Kerr "in this holiday infused lingerie runway show" taking place at the Fontainebleau Miami Beach and airing Dec. 3. Bells won't be the only thing jingling.

Jimmy Kimmel is making his fourth go-round at the American Music Awards, airing live on ABC Nov. 23. The producer calls Kimmel "a masterful host...audiences can expect a great night." Quips Kimmel: "I agree...completely."

Yet another degree of Kevin Bacon. His ubiquitous self will produce a new Showtime series, The Booths, centering on actor/assassin extraordinaire John Wilkes Booth and his thespian bros. No word yet whether Bacon will play a role.

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Casting Couch: Scorsese and De Niro Make a Killing

Robert De Niro, Martin Scorsese Evan Agostini/Getty Images

Big doings on the casting couch, what with Hayden Christensen remaining gainfully employed, 90210's Shenae Grimes getting a little extra cigarette money and somebody finally getting Yogi and Boo-Boo a film deal.

But that's nothing compared to this: Scorsese and De Niro are back in the crime biz.

The Oscar-owning buddies are joining cinematic forces for the ninth time—but their first collaboration since 1995's Casino—for Paramount's I Heard You Paint Houses, about the mob hitman believed to have 86'd Jimmy Hoffa.

Scorsese will helm the project and De Niro will play contract killer Frank "the Irishman" Sheeran, according to Variety. Sheeran murdered more than two dozen people at the behest of his Mafia bosses.

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Casting Couch: Swank's Latest Oscar Bait; Black's Bourne Goof; McBrayer Gets Revenge

Jack Black, Hilary Swank, Jack McBrayer Dave Hogan/Getty Images; Jason Kempin / Getty Images; Matthew Imaging / Getty Images

Sounds like it's time for Hilary Swank to start working on another Oscar speech. The actress is on the case in Betty Anne Waters, an Erin Brockovich-like drama based on a true story about a woman who fights to clear her brother of a murder he didn't commit. The flick will be helmed by director Tony Goldwyn (best known as the bad guy in Ghost), according to Variety.

Jack Black will be kickin' it in an untitled action-comedy for Universal. Taking a cue from The Bourne Identity, Black will play an American who awakes on a beach in Cuba with no idea who he is and how he got there and then mistakenly decides he's a superspy.

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Casting Couch: Diddy's Star Search; Demi's Sonny Days; Jesse's tru Calling

Sean "Diddy" Combs, Demi Lovato, Jesse Ventura Bennett Raglin/Getty Images, AP Photo

He's made the band. Now Diddy's looking to be a StarMaker. The hip-hop multihyphenate is teaming up with MTV and Survivor mastermind Mark Burnett for a new reality series. Taking the Idol formula one step further, StarMaker features solo artists trying to outperform each other while also dealing with photo ops, press interviews, paparazzi and living together. The premiere is set for January.

Now that she's back from her fab summer at Camp Rock, Demi Lovato is matriculating to Sonny With a Chance. The Disney Channel's family-friendly comedy series riffs on the Hannah Montana show-within-a-show concept with Lovato as a Midwestern teen cast in a sketch-comedy series. Nancy McKeon is on board in a recurring role, presumably to teach our dear Demi the facts of life.

Jesse Ventura ready to entertain us. He's been tapped to host a new, yet-to-be-titled series for truTV aiming to prove, or debunk, some of the world's greatest conspiracy theories. Let's start with how a former pro wrestler managed to get elected governor of Minnesota.

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Casting Couch: SMG Headed Back to TV

Sarah Michelle Gellar Sharkpixs/ZUMAPress.com

Buffy's ready to stake out some prime-time real estate again.

Sarah Michelle Gellar is set to star and executive produce the new HBO ensemble series The Wonderful Maladys, about three dysfunctional (are there any other kind in TV Land?) adult siblings living in New York and struggling to deal with the loss of their parents years ago.

Creator Charles Randolph tells Variety that he wrote the part with Gellar in mind. She'll play a woman with "a kind of zealous immaturity—like a drug addict with a to-do list."

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Casting Couch: Will Smith Still Is Legend; Opposite Attracts Hathaway; McAdams Sleuths Up Sherlock

Anne Hathaway, Will Smith, Rachel McAdams AP Photo/ Matt Sayles, Warner Bros. Entertainment, George Pimentel/Getty Images

He will survive...again. Probably to the chagrin of any movies aiming to open on Independence Day.

Warner Bros. is ramping up development on a prequel to the 2007 smash I Am Legend, which will see Will Smith reprising his role as one of the lone survivors on a zombified Earth.

Director Francis Lawrence is expected to take the reins again in the story of how New Yorkers came to be stricken by a deadly plague that turned them into nocturnal, blood-sucking creatures.

I Am Legend raked in $256 million domestically but [spoiler alert!] didn't really set up a Smith-starring sequel, prompting studio executives to start brainstorming other ways to keep the lucre flowing.

Meanwhile, in other Hollywood wheeling and dealing:

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Mickey Mouse News: Pirates, Tonto Ahoy for Depp; Oprah Pipes Up for Princess; Carrey Tops Carol

Johnny Depp Buena Vista Pictures

The entire Disney empire is turning into a one-man show. Luckily, that man is Johnny Depp.

The easy-on-the-eyes box-office heavyweight has signed on to appear in no less than three tentpole flicks for the Mouse House, chief among them reprising his Oscar-nominated role of Captain Jack Sparrow in a fourth installment of the Pirates of the Caribbean franchise.

In addition to the almost inevitable announcement of another Pirates go-round—during which the names Orlando Bloom and Keira Knightley went unmentioned—Disney also announced during a showcase event at the Kodak Theatre Wednesday that Depp would be joining the masked man in a remake of The Lone Ranger.

Depp will essay one of Hollywood's best-known sidekicks, Tonto.

And that's not all.

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Casting Couch: Affleck Gets Company; Crystal's New Fairy Tale

Ben Affleck Jeff Vespa/WireImage.com

Greed isn't so good for Ben Affleck.

Hollywood is looking to turn the economic meltdown into box-office gold, with Affleck in negotiations to topline The Company Men, as a victim of Wall Street's corporate downsizing.

ER's Emmy-winning writer-producer John Wells will make his feature-directing debut on the project, per the Hollywood Reporter, based on his own screenplay.

Next up for Affleck is the romcom He's Just Not That Into You, followed by the political thriller State of Play and the Mike Judge romp Extract.

In the day's other top deal doings:

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BIG PICTURE

Mummy and Me Gwen and two of her leading men hit the pumpkin patch for some Halloween prep

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  • Britney's "Womanizer" Music Video

    Be the first to catch a glimpse of Britney Spear's new "Womanizer" video.

  • Richie Kicks Butt on "Chuck"

    Former "Simple Life" star Nicole Richie packs a mean punch in her guest appearance on "Chuck." Check it out

  • Britney's "Fantasy" Fragrance

    Pop star Britney Spears adds "Hidden Fantasy" to her ever-growing perfume collection. Get the details.

  • Hollywood Rap-Up, Oct. 10

    Angelina Jolie debuts her post-baby bod, Jamie Lynn slams pregnancy rumors, Travis Barker gives thanks, more.